Bitter Orange Safety Concerns Are Overblown: study

A review of bitter orange safety was published in a peerr-reviewed journal. Analyzing the adverse event reports (AERs) submitted to the FDA, Sidney J. Stohs, dean emeritus of the Creighton University School of Pharmacy and Health Professions, reported that, “The belief that p-synephrine exerts serious cardiovascular and other events continues to be believed by the lay public as well as healthcare professionals, in spite of the lack of clearly defined supportive evidence for this supposition, as well as extensive evidence to the contrary.”



"An 8 oz glass of Californian mandarin orange juice may contain up to 35 mg p-synephrine (USDA). A sweet orange typically contains about 6 mg p-synephrine."


http://www.nutraingredients-usa.com/Industry/Bitter-orange-concerns-unwarranted-and-unjustified-Review/?c=Fe5usULeGc2A9I8d6ljtPw%3D%3D&utm_source=newsletter_daily&utm_medium=email&utm_campaign=Newsletter%2BDaily

Source: Journal of Functional Foods. Published online ahead of print, doi: 10.1016/j.jff.2010.10.003
“Assessment of the adverse event reports associated with Citrus aurantium (bitter orange) from April 2004 to October 2009” Author: S.J. Stohs