Sunday, June 29, 2008

Detoxification

Detoxification By Neil E. Levin, CCN, DANLA The EPA tracks about 650 toxic chemicals used in 23,600 facilities in the US. The agency reports that about half of the 4.24 billion pounds of these toxic chemicals are annually released into the air, ground or water. These include chemicals from the mining, smelting and power generation industries, paper production, electronic equipment manufacturing, plastics, pesticides, etc. While the highest release of chemicals is associated with mining and power production, other industries release problematic chemicals into the environment on a daily basis, all over our country. Certain groups are most at risk (e.g., children, pregnant and nursing women, the elderly). I would also add that people with multiple chemical exposures or even a single toxic level of exposure can develop a hyper-sensitivity to chemicals that can be debilitating. This condition is often called multiple chemical sensitivity. Of course, there is an increase in exposures as our exposure to so many chemicals uses up key nutrients and can overload the body’s ability to detoxify these toxic “insults” to the liver and other body systems. As our need for key nutrients and optimal detoxification processes grows during repeated, chronic exposures, our bodies may fail to keep pace and the levels of toxins can accumulate in our body. The results can be subtle (acne, headaches, persistent “colds”) or extreme (hair or tooth loss, chronic fatigue, pain). We see inflammatory-related conditions increasing, such as liver problems, cardiovascular issues, joint degradation and brain degeneration. While it is true that these conditions are associated with aging, it is also true that aging relates to the body’s inability to properly remove toxins and distribute nutrients to all of its tissues. Inflammatory chemicals can be either the original chemical or a biochemical metabolite that is produced in the body as a temporary step in neutralizing and removing the chemical. If inadequate nutrient stores do not allow the detoxification to complete - and often heroic levels of nutrients far above the RDI’s are required in these situations – then the body still will have a burden of toxic, inflammatory chemicals to contend with. The old adage is to reduce the exposure and increase the nutrients in order to allow the body to clear these toxins in its usual manner. Everything that lowers exposure, even removing shoes when entering a house or using appropriate filters for air ducts, may be helpful in reducing airborne toxins. But it is also important to reduce exposures through varied sources such as medications, non-organic food and the environment as best we can. Antioxidants, including sulfur-containing substances, are the key to detoxification. Methylation, sulfation and antioxidant reduction are some detoxification techniques used by the liver, especially. The liver utilizes these methods to render toxins inert enough to allow removal through the bile or the urine. Methylation can be enhanced by methyl donor nutrients, such as choline, TMG, DMG and SAMe. Sulfation is done with MSM, sulfur from plants (garlic, onions, broccoli, kale) or sulfur-containing proteins (methionine, cysteine, glutathione). Antioxidants include Vitamin C, alpha lipoic acid, etc. Any sources of these nutrients would be beneficial to aiding the body’s natural detoxification systems. One problem is that people often fear to use adequate, high levels of these nutrients, such as taking Vitamin C up to bowel tolerance levels. Some natural substances that enhance/support detoxification include Zinc, Selenium, Copper, Manganese, Sodium Alginate, Chlorella, Bladderwrack, MSM, Beet Root, Red Clover, Dandelion Root, Oregon Grape Root, and Milk Thistle Extract. Another new product is a broccoli seed concentrate called “sgs™”, which is backed by numerous clinical studies at Johns Hopkins regarding its ability to enhance natural detoxification. Adequate fiber is also important in moving the waste quickly through the colon to help remove toxins while avoiding exposure to toxins from the waste or from inappropriate microbes that fester in an unhealthy colon. Probiotics are important, especially bifidobacteria (Bifidus). Drinking adequate amounts of clean, filtered water is another must. Eating organic whenever possible is important, avoiding non-organic fruits and vegetables prone to heavy chemical exposure. Detoxification is a normal bodily function, so claiming that a dietary supplement can support this function would be a legitimate “structure-function statement” authorized by federal law if the clinical documentation is available. Neil E. Levin, CCN, DANLA is a nationally certified clinical nutritionist with a Diplomate in Advanced Nutritional Laboratory Assessment. He is a professional member of the International & American Associations of Clinical Nutritionists. Neil is the nutrition education manager and a product formulator for NOW Foods, a natural food and dietary supplement manufacturer in Bloomingdale, Illinois. Neil is a member of the Scientific Council of the national Clinical Nutrition Certification Board and serves on the board of directors of the Mid-American Health Organization (MAHO), the Midwest regional affiliate of the National Products Association (formerly NNFA). Neil is routinely interviewed for articles in trade magazines serving the natural products industry and has published articles in magazines and newspapers, contributed to scientific journals and has been a guest on numerous radio shows. He has been interviewed for television news reports many times over a 33-year career. You can read some of Neil’s recent articles at his non-commercial website: http://www.honestnutrition.com/

Cardiovascular Health

Cardiovascular Health By Neil E. Levin, CCN, DANLA For a healthy cardiovascular system it is important to get plenty of nutrients over the whole range. B-Vitamins, for example, help to produce energy and to control metabolic processing, including the one that results in excessive levels of the inflammatory compound homocysteine. Homocysteine is a greater risk factor for cardiovascular risk than total cholesterol level. Antioxidants support each other, and clinical research indicates that total antioxidant status is more important than a single level of a single antioxidant nutrient. Antioxidants protect cholesterol from oxidizing, and also protect arterial surfaces from being damaged, leading to plaque formation and cholesterol “patches”. Minerals are also useful for cholesterol metabolism - especially chromium - also calcium, copper, and possibly magnesium and selenium. With the recent stories about obese children – some with Type-2 “adult-onset” diabetes - and with kids getting heart attacks in their teens, there is a growing awareness that cardiovascular health issues are not limited to middle aged men. Recent reports also point to the increased risk for women after menopause or who are on hormone replacement drugs, hammering the point home that age and gender are no longer rigid dividers of people into cardiovascular risk groups. That’s not to say that everyone is aware of these cardiovascular risk factors, but the risk categories in terms of age have certainly broadened dramatically in recent years. We have seen an increasing number of college-aged young men be afflicted by cardiac events at sports or training events, with some dying. Still, the risks do not seem as immediate to young adults with their heightened sense of immortality, especially young men. By the time men hit their 40s, there is an increased awareness of cardiac risks that keeps increasing throughout their lives. The young are mostly oblivious to health risks unless some event creates the beginnings of awareness that they may be at risk, such as a close relative suffering a cardiac event at an early age or a health scare. Unfortunately, these events seem to be increasing. Genetics, sedentary lifestyles, poor diet and obesity all make people susceptible to vascular problems. The emergence of hemorrhoids or any hint of varicose veins should be obvious indications of cardiovascular weakness at any age. Obesity and lack of stamina are also good indicators. Family health history is another consideration that should affect awareness. Circulation depends on body movement/exercise and requires an unobstructed blood flow through flexible blood vessels that have structural integrity. Collagen, elastin and supporting nutrients (proline, lysine, Vitamin C, Pycnogenol®, rutin) help to strengthen these tissues, while certain herbs (cayenne, garlic, horse chestnut, prickly ash extract, hawthorn extract) help to improve blood flow. Smoking and stress narrow the blood vessels, increasing the risk of forming clots or obstructions. Certain amino acids in the diet (arginine, citrulline) support NO (nitric oxide) formation that dilates blood vessels to reduce blood pressure and enhance blood flow to the peripheries. The presence of these components and modulators in the diet help to maintain cardiovascular health and vascular integrity. People should be eating a variety of fruits and vegetables, along with whole grains, in order to provide nutrients essential to the integrity of blood vessels. Products in the Cholesterol/Cardiovascular Support category include plant sterols (containing beta sistosterol), ascorbyl palmitate, Vitamin E, chromium, garlic, guar gum, Guggul extract, tocotrienols, policosanol, B1, B6, folate, B12, iodine, magnesium, selenium, potassium, garlic, carnitine, ginger, cayenne, hawthorn extract, CoQ10, alpha lipoic acid, TMG, Red Yeast Rice Extract, prickly ash extract, horse chestnut extract, butcher’s broom extract, grape seed extract rutin, nattokinase (fibrin enzyme for supporting the body’s control of clotting), fish oil, lecithin, Pycnogenol®, as well as hawthorn leaf and flower extract. Remember, you must take care of your heart and cardiovascular system if you expect them to take care of you for a lifetime! Neil E. Levin, CCN, DANLA is a nationally certified clinical nutritionist with a Diplomate in Advanced Nutritional Laboratory Assessment. He is a professional member of the International & American Associations of Clinical Nutritionists. Neil is the nutrition education manager and a product formulator. Neil is a member of the Scientific Council of the national Clinical Nutrition Certification Board and serves on the board of directors of the Mid-American Health Organization (MAHO), the Midwest regional affiliate of the National Products Association (formerly NNFA). Neil is routinely interviewed for articles in trade magazines serving the natural products industry and has published articles in magazines and newspapers, contributed to scientific journals and has been a guest on numerous radio shows. He has been interviewed for television news reports many times over a 36-year period. You can read some of Neil’s recent articles at his non-commercial website: http://www.honestnutrition.com/